Considerable literature reflects the supposition that the earlier in life one is exposed to nicotine, the more likely one is to become addicted to its effects, just as the earlier one is exposed to alcohol, the greater the threat of alcoholism pursuant to repeated substance exposure. While there may indeed be some underlying genetic influences, the literature provides contradictory evidence of households where adults are afflicted with nicotine addiction and children and adolescents in that household are not. Neither does the contemporary research point to gender as a basis for predicting nicotine addiction. Considering the inability of prior research to do little more than support the ongoing stigmatization of abuse of addictive substances across the spectrum of stimulants on the grounds of race, gender, environment, genetics, behavioral anomalies, delinquency, and socio-economics, there is little wonder that the nutritional sciences are beginning to receive increased attention among researchers investigating the root causes of nicotine addiction. If those aforementioned issues are not the causes of nicotine addiction, as established by the failure of any conclusive determination based upon the research literature in that regard, the working presumption of underlying biochemical phenomena rises from the ashes. The human corporeal experience is ultimately the product of biochemical activity within the body along a “metabolic pathway” where metabolites are subject to myriad chemical reactions driven by enzyme activity driven by dietary minerals, vitamins, and amino acid breakdowns. These chemical reactions are fueled by the digestive breakdown of carbohydrates, fats, and proteins, the molecular components of which enter the metabolic pathway. This tricarboxylic acid cycle and the chemical energy produced by it is fundamental to the efficiency of our individual metabolic functioning. Insofar as these metabolic cycles are variable among phyla and species, there may be the potential for variability within a single genetic group, i.e., a family living in the same house. Individual biochemical imbalance, then, may be the determinative factor leading to nicotine addiction, pursuant to individualized hormone imbalances affecting neurotransmitter activity. These underlying biochemical imbalances can be either exacerbated or mitigated by the nutrients provided to our individual metabolic pathway and its molecular processes (Hyman). Current nutritional research points to the efficacy of a diet focused upon the correction of those hormonal imbalances underlying dysfunctional neurologic activity which lead to nicotine abuse and the difficulties of overcoming its addictive compulsions. Because the same metabolic processes that break down carbohydrates, proteins, and fats providing the fuels and nutrients for the functioning of our motor and autonomous systems also provide the molecular power to drive our neurotransmitters, when we eat, we are feeding our brains as much as we’re feeding our “body”.