It's been about 6 months now since my transplant. I was having kidney issues so I was diminishing tacrolimus, (0.5 mg twice a day) , whilst moving to sirolimus. Not long after the two month point of confinement had passed, the prednisolone, which has been step by step decreased to 5 mg was withdrawn. I was truly satisfied for a while, until I got the shakes, headaches, tiredness, a bit of agony in the liver area & for the most part I felt very unwell. I felt so wiped out I nearly blacked out, and for a considerable length of time everything I could do was shake and cry, I scarcely ever ate. Did any other person feel so wiped out ?