Usually, it's negative thoughts that make people feel miserable and many, to block the thoughts will choose to use drugs but this doesn't help because once the effect of the drug has worn off the intrusive thoughts will be back. If you continue self-soothing with drugs, your addiction problem gets worse. The better solution therefore would be to find ways to block out the negative thoughts. There are a few who suggest thinking about something different, something nice but this doesn't work all the time. Any suggestions?